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Chicago Cubs baseball all-time roster of players with the last name starting with the letter “I.”
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| Blaise Ilsley | P | 1994 |
| Monte Irvin | OF | 1956 |
| Charlie Irwin | SS | 1893-1895 |
| Frank Isbell | OF | 1898 |
| Cesar Izturis | SS | 2006-2007 |